Fig. 1 · Structure
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Nicotinanilide
AQP4 Inhibitor
Nicotinanilide is an aquaporin 4 (AQP4) inhibitor that demonstrates significant biological activity in modulating water transport across cell membranes. This compound is particularly relevant for research focused on neurological disorders associated with AQP4 dysfunction, including epilepsy and migraine. Its inhibition of AQP4 provides a valuable tool for investigating the underlying mechanisms of these conditions and exploring potential therapeutic strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1752-96-1 |
| Applications | AQP4 Inhibitor |
| Formula | C12H10N2O |
| Molecular Weight | 198.23 |
| Synonyms | N-Phenylnicotinamide |
| SMILES | O=C(NC=1C=CC=CC1)C=2C=NC=CC2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.