Ningetinib

Catalog No.: A17042

tyrosine kinase inhibitor

Ningetinib

Ningetinib Chemical Structure

CAS NO. 1394820-69-9

Ningetinib is a multi-kinase inhibitor that inhibits c-Met, VEGFR2/KDR, and Axl with IC50s value of 19, 37, and 11 nM, respectively.

Availability: In stock

Package Price Qty
5 mg
$120.00
10 mg
$200.00
50 mg
$780.00
100 mg
$1,280.00
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Biological Activity

Ningetinib is a multi-kinase inhibitor that inhibits c-Met, VEGFR2/KDR, and Axl with IC50s value of 19, 37, and 11 nM, respectively.
In vitro DMSO 18 mg/mL (32.34 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.97 mL 89.83 mL 179.66 mL
0.5 mM 3.59 mL 17.97 mL 35.93 mL
1 mM 1.8 mL 8.98 mL 17.97 mL
5 mM 0.36 mL 1.8 mL 3.59 mL

*The above data is based on the productmolecular weight 556.6. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A17042
Actions Inhibitor
CAS No. 1394820-69-9
Formula C31H29FN4O5
M. Wt 556.6
Purity >98%
SMILES FC1=CC(NC(C2=C(C)N(C)N(C3=CC=CC=C3)C2=O)=O)=CC=C1OC4=CC=NC5=C4C=CC(OCC(O)(C)C)=C5
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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