Fig. 1 · Structure
Documents & Downloads
Niraparib metabolite M1
Cat. No.
A70153
CAS
1476777-06-6
Drug Metabolite
Niraparib metabolite M1 is a bioactive metabolite of the poly(ADP-ribose) polymerase (PARP) inhibitor niraparib. This compound retains the biological effects associated with PARP inhibition, contributing to the understanding of niraparib's pharmacokinetics and pharmacodynamics. Niraparib metabolite M1 is relevant for investigating the mechanisms of action and therapeutic effects of PARP inhibitors in cancer research, particularly in the context of DNA repair and cellular response to genotoxic stress.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1476777-06-6 |
| Applications | Drug Metabolite |
| Formula | C19H19N3O2 |
| Molecular Weight | 321.37 |
| Synonyms | Niraparib carboxylic acid metabolite M1; M1 metabolite of niraparib |
| SMILES | O=C(C1=CC=CC2=CN(C3=CC=C([C@H]4CNCCC4)C=C3)N=C12)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.