Fig. 1 · Structure
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Nitroparacetamol
NO Donor-NSAID
Nitroparacetamol is a nitric oxide (NO) donor and non-steroidal anti-inflammatory agent (NO-NSAID) designed to enhance the analgesic properties of Acetaminophen through ester linkage with Nitrooxybutyroyl. It exhibits a broad analgesic spectrum effective against various painful conditions while offering organ-protective benefits, specifically reducing hepatotoxicity. Nitroparacetamol modulates inflammatory responses by decreasing the expression levels of key cytokines and enzymes, including IL-1β, TNF-α, COX-2, and iNOS, making it a valuable tool for research in pain management and inflammation biology.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 326850-30-0 |
| Applications | NO Donor-NSAID |
| Formula | C12H14N2O6 |
| Molecular Weight | 282.25 |
| Synonyms | NCX-701 |
| SMILES | O=C(CCCO[N+]([O-])=O)OC1=CC=C(C=C1)NC(C)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.