Fig. 1 · Structure
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NJH-2-030
E3 Ligase Ligand-Linker Conjugates Chemical
NJH-2-030 is a specialized E3 ligase ligand-linker conjugate that facilitates targeted protein degradation through covalent recruitment of FEM1B. This compound is essential for exploring targeted protein degradation pathways and studying the dynamics of protein interactions in various biological contexts. Its application is particularly relevant in the fields of drug discovery and therapeutic development, where precise modulation of protein levels is crucial.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2709040-02-6 |
| Applications | E3 Ligase Ligand-Linker Conjugates Chemical |
| Formula | C19H20ClN3O3 |
| Molecular Weight | 373.83 |
| SMILES | C#CCCCC(N1CCOC2=C1C=CC(N(C(CCl)=O)CCC#N)=C2)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.