Fig. 1 · Structure
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NLG802
Indoximod Prodrug
NLG802 is a prodrug of indoximod, functioning as an inhibitor of indoleamine 2,3-dioxygenase (IDO). This compound enhances systemic immunity by modulating the immune response through IDO inhibition. NLG802 is of particular interest in cancer research, where it may improve the efficacy of immune checkpoint therapies and promote antitumor activity.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2071683-99-1 |
| Applications | Indoximod Prodrug |
| Formula | C20H30ClN3O3 |
| Molecular Weight | 395.92 |
| SMILES | CC(C)C[C@H](N)C(N[C@@H](C(OCC)=O)CC1=CN(C)C2=CC=CC=C12)=O.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.