Fig. 1 · Structure
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NM102
Mfd Protein Inhibitor
NM102 is an ATP-competitive inhibitor of the mutation frequency decline (Mfd) protein, demonstrating an IC50 value of 29 μM and a Ki of 27 μM. This compound exhibits significant antimicrobial activity, particularly against antimicrobial-resistant ESKAPE pathogens. NM102 shows efficacy in insect and mouse models, making it a valuable tool for studying infections caused by Gram-negative bacteria. Its unique mechanism and biological activity position NM102 as a key reagent in infectious disease research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2094576-12-0 |
| Applications | Mfd Protein Inhibitor |
| Formula | C20H24N4O5S2 |
| Molecular Weight | 464.56 |
| SMILES | O=C1NC2=C(N1C3CCN(S(=O)(C4=CC=C(S(=O)(N(C)C)=O)C=C4)=O)CC3)C=CC=C2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.