NMDA receptor potentiator-1

Catalog No.: A67289
NMDA Receptor Potentiator
NMDA receptor potentiator-1 is a selective modulator targeting the NMDA receptor, specifically enhancing the activity of NR2C and NR2D subunits with IC50 values of 4 μM and 5 μM, respectively. This compound shows promise in increasing synaptic transmission and may serve as a valuable tool in studies related to neuropharmacology, synaptic plasticity, and neurodegenerative diseases. Its selective mechanism of action makes it a suitable candidate for investigating receptor-specific pathways and potential therapeutic applications.
Grouped product items
Size Price Stock Qty
25mg
$1,275.00
In stock
50mg
$1,625.00
In stock
100mg
$2,000.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionNMDA receptor potentiator-1 is a selective modulator targeting the NMDA receptor, specifically enhancing the activity of NR2C and NR2D subunits with IC50 values of 4 μM and 5 μM, respectively. This compound shows promise in increasing synaptic transmission and may serve as a valuable tool in studies related to neuropharmacology, synaptic plasticity, and neurodegenerative diseases. Its selective mechanism of action makes it a suitable candidate for investigating receptor-specific pathways and potential therapeutic applications.
Product Information
Catalog NumA67289
FormulaC26H26ClNO5
Molecular Weight467.94
CAS Number486427-18-3
SMILESO=C(N1CCC2=CC(OC)=C(C=C2C1COC3=CC=C(C=C3)OC)OC)C4=CC=C(C=C4)Cl
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