Fig. 1 · Structure
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NMDAR antagonist 1
iGluR Antagonist
NMDAR Antagonist 1 is a selective antagonist of the NR2B subunit of the N-Methyl-D-Aspartate receptor (NMDAR). This compound demonstrates significant inhibitory activity, making it valuable for research into neurological disorders linked to NMDA receptor dysregulation. Its oral bioavailability facilitates in vivo applications, enhancing the potential for therapeutic exploration in conditions such as pain, depression, and neurodegeneration.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 2220162-06-9 |
| Applications | iGluR Antagonist |
| Formula | C20H20BrN3O2 |
| Molecular Weight | 414.30 |
| SMILES | O=C(NCCC1=CC=C(O)C=C1)[C@@H]2CCC3=NC4=CC=C(Br)C=C4CN32 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.