Catalog No.: A14292

HSP90 inhibitor


NMS-E973 Chemical Structure

CAS NO. 1253584-84-7

NMS-E973 is a potent and selective Hsp90 inhibitor.

Availability: In stock

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5 mg
10 mg
25 mg
10mM * 1mL in DMSO
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Biological Activity

NMS-E973 is a potent and selective Hsp90 inhibitor.
<10 nM(DC50)
In vitro DMSO Warmed: 78 mg/mL (171.64 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.01 mL 110.03 mL 220.06 mL
0.5 mM 4.4 mL 22.01 mL 44.01 mL
1 mM 2.2 mL 11 mL 22.01 mL
5 mM 0.44 mL 2.2 mL 4.4 mL

*The above data is based on the productmolecular weight 454.43. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A14292
Actions Inhibitor
CAS No. 1253584-84-7
Formula C22H22N4O7
M. Wt 454.43
Purity >98%
Synonyms NMS E973,NMSE973
SMILES CN1CCC(CC1)NC(=O)C2=C/C(=C\3/C(=CC(=O)C=C3OC4=CC=C(C=C4)[N+](=O)[O-])O)/ON2

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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