NMT-IN-7 is a potent inhibitor of N-myristoyl transferase (NMT), exhibiting IC50 values of 2.1 nM for HsNMT1M and 0.6 nM for SU-DHL-10 cells. This compound functions effectively as an antibody-drug conjugate (ADC) cytotoxin, demonstrating significant potential in targeted cancer therapy. Its selective inhibition of NMT may facilitate the study of myristoylation in biological processes and contribute to the development of novel therapeutic strategies.
NMT-IN-7 is a potent inhibitor of N-myristoyl transferase (NMT), exhibiting IC50 values of 2.1 nM for HsNMT1M and 0.6 nM for SU-DHL-10 cells. This compound functions effectively as an antibody-drug conjugate (ADC) cytotoxin, demonstrating significant potential in targeted cancer therapy. Its selective inhibition of NMT may facilitate the study of myristoylation in biological processes and contribute to the development of novel therapeutic strategies.
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