Fig. 1 · Structure
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NO-Losartan A
Slow NO Donor
NO-Losartan A is a slow nitric oxide (NO) donor that exhibits significant vasorelaxing effects through the sustained release of NO. This compound effectively antagonizes the vasocontractile actions of Angiotensin II, showing potencies comparable to Losartan. NO-Losartan A is valuable in research applications focused on cardiovascular pharmacology and the modulation of vascular tone.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 791122-48-0 |
| Applications | Slow NO Donor |
| Formula | C30H28ClN7O5 |
| Molecular Weight | 602.04 |
| SMILES | O=C(OCC1=C(Cl)N=C(CCCC)N1CC2=CC=C(C3=CC=CC=C3C4=NNN=N4)C=C2)C5=CC=CC(CO[N+]([O-])=O)=C5 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.