Fig. 1 · Structure
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Nolomirole hydrochloride
DA2 Receptor/α2-Adrenoceptor Agonist
Nolomirole hydrochloride is a selective agonist of the DA2 dopaminergic receptor and α2-adrenoceptor. This compound has demonstrated the ability to mitigate signs of heart failure in the monocrotaline-induced congestive heart failure model. By enhancing cardiac output, Nolomirole hydrochloride serves as a valuable tool for research into cardiac function and potential therapeutic interventions in heart failure.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 138531-51-8 |
| Applications | DA2 Receptor/α2-Adrenoceptor Agonist |
| Formula | C19H28ClNO4 |
| Molecular Weight | 369.88 |
| Synonyms | CHF 1035 |
| SMILES | CC(C)C(OC1=C2C(CC(NC)CC2)=CC=C1OC(C(C)C)=O)=O.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.