Fig. 1 · Structure
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Nolomirole
DA2 Receptor/α2-Adrenoceptor Agonist
Nolomirole is a selective agonist for the dopamine D2 receptor and the α2-adrenoceptor. It has demonstrated the ability to mitigate heart failure symptoms in models induced by Monocrotaline, such as improved cardiac output. This compound offers valuable insights for research into therapeutic strategies for cardiac dysfunction and heart failure.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 90060-42-7 |
| Applications | DA2 Receptor/α2-Adrenoceptor Agonist |
| Formula | C19H27NO4 |
| Molecular Weight | 333.42 |
| Synonyms | CHF 1035 free base |
| SMILES | CC(C)C(OC1=C2C(CC(NC)CC2)=CC=C1OC(C(C)C)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.