Fig. 1 · Structure
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Nonabine
CB1 Receptor Activator
Nonabine (BRL-4664) is a cannabinoid that selectively activates the CB1 receptor, primarily targeting the brainstem and enteric nervous system. This compound exhibits significant antiemetic properties, making it valuable for research focused on nausea and vomiting mechanisms. Its ability to modulate cannabinoid receptors provides insight into potential therapeutic applications for gastrointestinal disorders and central nervous system regulation.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 16985-03-8 |
| Applications | CB1 Receptor Activator |
| Formula | C25H33NO2 |
| Molecular Weight | 379.54 |
| Synonyms | BRL-4664 |
| SMILES | OC1=C2C(C3=CC=NC=C3)=CC(C)(OC2=CC(C(C(CCCCC)C)C)=C1)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.