Fig. 1 · Structure
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nor-Binaltorphimine
Kappa-opioid Receptor Antagonist
Nor-Binaltorphimine is a selective antagonist of the kappa-opioid receptor, known for its role in modulating nociception and mood regulation. This compound exhibits prolonged effects in vivo, making it a valuable tool in research related to pain management, addiction, and psychiatric disorders. Its specificity for kappa-opioid receptors supports studies focused on understanding their physiological and pathological roles.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 105618-26-6 |
| Applications | Kappa-opioid Receptor Antagonist |
| Formula | C40H43N3O6 |
| Molecular Weight | 661.79 |
| Synonyms | NorBNI |
| SMILES | O[C@]12[C@]34[C@](OC5=C(O)C=CC(C[C@@]2([H])N(CC4)CC6CC6)=C53)([H])C7=C(C8=C([C@@]9([H])[C@]%10%11[C@@](C8)([C@](CC%12=C%11C(O9)=C(C=C%12)O)([H])N(CC%10)CC%13CC%13)O)N7)C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.