Fig. 1 · Structure
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NorA-IN-1
NorA Inhibitor
NorA-IN-1 is a selective inhibitor of the NorA efflux pump, known for its role in mediating multidrug resistance in bacteria. This compound has demonstrated effectiveness in inhibiting the NorA pump in everted membrane vesicles, making it a valuable tool for studying the mechanisms of antibiotic resistance and the potential for overcoming it in microbial pathogens. Research applications include exploring strategies to enhance the efficacy of antimicrobial agents against resistant bacterial strains.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1389310-69-3 |
| Applications | NorA Inhibitor |
| Formula | C18H18O5 |
| Molecular Weight | 314.33 |
| SMILES | O=C(C1=CC=C(C=C1)O)/C=C/C2=C(OC)C=C(OC)C=C2OC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.