Fig. 1 · Structure
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(+)-Norcisapride
5-HT4 Agonist/5-HT3 Antagonist
(+-Norcisapride) functions primarily as a 5-HT4 agonist and a 5-HT3 antagonist. This compound exhibits significant biological activity in promoting gastrointestinal motility and has demonstrated effectiveness in animal models of constipation. It is a valuable reagent for research focused on gastrointestinal disorders and the modulation of serotonergic signaling pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 202590-69-0 |
| Applications | 5-HT4 Agonist/5-HT3 Antagonist |
| Formula | C14H20ClN3O3 |
| Molecular Weight | 313.78 |
| Synonyms | Ticalopride |
| SMILES | O=C(N[C@H]1[C@@H](OC)CNCC1)C2=CC(Cl)=C(N)C=C2OC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.