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Norketotifen

Ketotifen Active Metabolite

Norketotifen, the active metabolite of Ketotifen, primarily targets inflammation pathways. It demonstrates significant anti-inflammatory, antipruritic, and anti-malarial activities. Norketotifen effectively inhibits TNF-α release, making it a valuable tool for research on non-sedating anti-inflammatory agents, particularly in models of allergic responses and skin conditions. This compound is particularly useful for studies focused on non-histamine-mediated itching and inflammation.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	34580-20-6
Applications	Ketotifen Active Metabolite
Formula	C₁₈H₁₇NOS
Molecular Weight	295.40
SMILES	O=C1C2=C(/C(C3=C(C1)C=CC=C3)=C4CCNCC\4)C=CS2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.