Fig. 1 · Structure
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Nortriptyline
Antidepressant
Nortriptyline, a tricyclic antidepressant and the primary active metabolite of Amitriptyline, primarily targets serotonin and norepinephrine reuptake transporters. This compound exhibits notable biological activity as an autophagy inhibitor, contributing to its potential anticancer effects. It is widely utilized in both depression therapy and cancer research to explore its multifaceted biological mechanisms.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 72-69-5 |
| Applications | Antidepressant |
| Formula | C19H21N |
| Molecular Weight | 263.38 |
| Synonyms | Desmethylamitriptyline; Desitriptilina |
| SMILES | CNCC/C=C1C2=CC=CC=C2CCC3=CC=CC=C\13 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.