Noscapine-13C,d3

Catalog No.: A32696
Stable Isotope
Noscapine-13C,d3 is a stable isotope-labeled form of noscapine, a phthalideisoquinoline alkaloid known for its potent antitussive properties. This compound primarily acts by engaging sigma opioid receptors and serves as a non-competitive inhibitor of bradykinin. In addition to its antitussive effects, noscapine disrupts microtubule dynamics, induces mitotic arrest, and promotes apoptosis, showcasing significant anticancer, neuroprotective, and anti-inflammatory activities. Its ability to cross the blood-brain barrier makes it suitable for a variety of biological research applications.
Grouped product items
Size Price Stock Qty
500µg
$175.00
In stock
1mg
$330.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
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Nature Volume 622 Issue 7982 (2023)
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Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
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Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionNoscapine-13C,d3 is a stable isotope-labeled form of noscapine, a phthalideisoquinoline alkaloid known for its potent antitussive properties. This compound primarily acts by engaging sigma opioid receptors and serves as a non-competitive inhibitor of bradykinin. In addition to its antitussive effects, noscapine disrupts microtubule dynamics, induces mitotic arrest, and promotes apoptosis, showcasing significant anticancer, neuroprotective, and anti-inflammatory activities. Its ability to cross the blood-brain barrier makes it suitable for a variety of biological research applications.
Product Information
Catalog NumA32696
FormulaC2113CH20D3NO7
Molecular Weight417.43
CAS Number1217680-57-3
SMILESCOC1=C(OCO2)C2=CC3=C1[C@@]([C@]4([H])C5=CC=C(OC)C(OC)=C5C(O4)=O)([H])N(CC3)[13C]([2H])([2H])[2H]
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