Fig. 1 · Structure
Documents & Downloads
Noscapine hydrochloride
Antitussive Agent
Noscapine hydrochloride primarily targets sigma opioid receptors, serving as an effective antitussive agent. This phthalideisoquinoline alkaloid exhibits significant biological activities, including the disruption of microtubule dynamics, induction of mitotic arrest, and apoptosis. Additionally, it demonstrates anticancer properties along with neuroprotective and anti-inflammatory activities, and is capable of crossing the blood-brain barrier, making it valuable for diverse research applications in oncology and neuroscience.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 912-60-7 |
| Applications | Antitussive Agent |
| Formula | C22H24ClNO7 |
| Molecular Weight | 449.88 |
| Synonyms | (S,R)-Noscapine hydrochloride |
| SMILES | O=C1O[C@H]([C@@H]2N(C)CCC3=C2C(OC)=C(OCO4)C4=C3)C5=C1C(OC)=C(OC)C=C5.[H]Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.