Fig. 1 · Structure
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NOTA-P2-RM26
Bombesin Analog
NOTA-P2-RM26 is a Bombesin analog that functions as an antagonist of the gastrin-releasing peptide receptor (GRPR/BB2), making it a valuable tool for prostate cancer imaging. This compound is labeled with 111In and 68Ga, facilitating advanced imaging techniques such as PET and SPECT/CT. It is particularly useful in the visualization and research of prostate cancer, aiding in the development of targeted therapies and diagnostic strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 1446005-10-2 |
| Applications | Bombesin Analog |
| Formula | C73H110N18O19 |
| Molecular Weight | 1543.76 |
| SMILES | C([C@H](NC([C@@H](NC([C@@H](CC1=CC=CC=C1)NC(COCCOCCNC(CN2CCN(CC(O)=O)CCN(CC(O)=O)CC2)=O)=O)=O)CCC(N)=O)=O)C(N[C@H](C(N[C@H](C(NCC(N[C@@H](CC3=CN=CN3)C(N[C@H]([C@H](CC(N[C@@H](CC(C)C)C(N)=O)=O)O)CC(C)C)=O)=O)=O)[C@H](C)C)=O)C)=O)C=4C=5C(NC4)=CC=CC5 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.