Fig. 1 · Structure
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Notch 1
Notch 1
Notch 1 is a Type I transmembrane protein that belongs to the NOTCH family, characterized by its extracellular domain containing multiple epidermal growth factor-like (EGF) repeats and a diverse intracellular domain structure. It plays a critical role in regulating cell differentiation, proliferation, and apoptosis through its involvement in cell-cell communication. Research applications include studies on developmental biology, cancer, and immune response, making Notch 1 a key target for understanding various signaling pathways and therapeutic interventions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2408730-51-6 |
| Applications | Notch 1 |
| Formula | C62H97N15O22S3 |
| Molecular Weight | 1500.72 |
| SMILES | [C@H](CC1=CC=CC=C1)(C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCC(O)=O)C(O)=O)=O)CS)=O)[C@H](CC)C)=O)CS)=O)CCC(N)=O)=O)NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CS)N)=O)CC(C)C)=O)CC(O)=O)=O)CCC(N)=O)=O)[C@H](CC)C)=O)=O)CCC(O)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.