Fig. 1 · Structure
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NPD926
ROS Activator
NPD926 is a small molecule that acts as a reactive oxygen species (ROS) activator. By depleting intracellular glutathione levels, NPD926 promotes the generation of ROS, which can lead to apoptosis in cancer cells. This compound has potential applications in cancer research, particularly in enhancing the efficacy of Xc- system inhibitors in fibrotic conditions. NPD926 serves as an important tool for investigating ROS-related signaling pathways in cancer biology.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Activator |
| CAS Number | 384361-79-9 |
| Applications | ROS Activator |
| Formula | C29H35ClN2O2 |
| Molecular Weight | 479.05 |
| SMILES | CC(OC1=CC=C(C=C1)C(C2=CC=CC=C2)CCN(CC3=CC=C(C=C3)N(C)C)C(CCl)=O)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.