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NPI52

FMDV 3Cpro Inhibitor

NPI52 is an inhibitor of foot-and-mouth disease virus 3C protease (FMDV 3Cpro), exhibiting potent inhibitory activity with IC50 values of 0.05 µM in FRET assays and 0.11 µM in cell-based assays. It serves as a valuable tool for investigating the mechanisms of viral replication and can aid in the development of antiviral strategies against foot-and-mouth disease. NPI52 is essential for researchers studying FMDV protease-targeted therapeutics and the broader field of viral protease inhibition.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	1429218-68-7
Applications	FMDV 3Cpro Inhibitor
Formula	C₃₄H₄₀N₄O₆
Molecular Weight	600.70
SMILES	O=C(N[C@@H](CC1=C(C=CC=C2)C2=CC=C1)C(N[C@@H](CC(C)C)C(N[C@@H](C[C@H]3C(NCC3)=O)C=O)=O)=O)OCC4=CC=CC=C4

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.