Fig. 1 · Structure
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NPP1-IN-1
NPP Inhibitor
NPP1-IN-1 is a selective inhibitor of nucleoside triphosphate diphosphohydrolase-1 (NPP1), exhibiting an IC50 of 0.15 μM. It also demonstrates activity against NPP3 with an IC50 of 40 μM. This compound serves as a valuable tool for research applications in cell signaling and metabolic regulation, enabling the investigation of NPP1-related pathways and their implications in various diseases.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2493063-65-1 |
| Applications | NPP Inhibitor |
| Formula | C27H21NO2 |
| Molecular Weight | 391.46 |
| SMILES | CCOC1=CC=CC=C1C2=NC(C3=CC=C(C4=C5C=CC=CC5=CC=C4)C=C3)=CO2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.