Fig. 1 · Structure
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NR4A agonist-1
NR4A Agonist
NR4A agonist-1 is a potent agonist targeting NR4A receptors, specifically Nurr1, Nur77, and NOR-1. It exhibits strong agonist activity with EC50 values of 0.09 μM, 0.04 μM, and 0.15 μM, respectively. This compound is valuable for research applications focused on NR4A signaling pathways, which are implicated in various cellular processes, including inflammation and metabolism.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 360778-55-8 |
| Applications | NR4A Agonist |
| Formula | C14H10Cl2O3 |
| Molecular Weight | 297.13 |
| SMILES | O=C(C1=CC(OCC2=CC=C(C=C2Cl)Cl)=CC=C1)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.