Fig. 1 · Structure
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NRG1271
mPTP Inhibitor
NRG1271 is an orally active inhibitor of the mitochondrial permeability transition pore (mPTP) that effectively penetrates the blood-brain barrier. This compound demonstrates significant neuroprotective properties, making it a valuable tool for investigating various neurological diseases and disorders. Its ability to modulate mitochondrial function positions NRG1271 as a key reagent in research focused on neurodegeneration and related pathologies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 3077720-24-9 |
| Applications | mPTP Inhibitor |
| Formula | C17H13F3N4O |
| Molecular Weight | 346.31 |
| SMILES | FC1=C2C(C=NN2)=CC=C1/C=C(F)/C(NC3=C(C)N=CC(F)=C3C)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.