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NRMA-10

Nuclear Receptor Modulator

NRMA-10 is a brain-penetrant nuclear receptor modulator designed as an amide prodrug. It significantly enhances the expression of Adam10 in the brain, demonstrating a preferential distribution to the central nervous system over peripheral tissues. This compound is applicable in research focused on central nervous system disorders, enabling the exploration of potential therapeutic strategies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Modulator
CAS Number	2375659-17-7
Applications	Nuclear Receptor Modulator
Formula	C₂₀H₂₀N₂OS
Molecular Weight	336.45
SMILES	O=C(C1=CN=C(C=C1)C#CC2=CC=C3SCCC(C)(C)C3=C2)NC

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.