Fig. 1 · Structure
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NRP1 antagonist 1
NRP1 Antagonist
NRP1 antagonist 1 is a potent antagonist of neuropilin-1 (NRP1) with an IC50 of 19.1 μM. This compound exhibits significant promise in cancer research by inhibiting NRP1-mediated signaling pathways that contribute to tumor progression and metastasis. Its application in preclinical studies can further elucidate the role of NRP1 in various cancer types and support the development of targeted therapies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 2569598-01-0 |
| Applications | NRP1 Antagonist |
| Formula | C22H22N6OS2 |
| Molecular Weight | 450.58 |
| SMILES | O=C(NC1=NN=C(CC)S1)CSC2=NN=C(C3=CC=C(C)C=C3)N2C4=CC=CC(C)=C4 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.