Fig. 1 · Structure
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NS 9283
α4β2 nAChR Agonist
NS 9283 is a positive allosteric modulator of the α4β2 nicotinic acetylcholine receptors (nAChR). It enhances receptor activity, making it useful for studying neurological conditions such as attention deficit hyperactivity disorder (ADHD), schizophrenia, Parkinson's disease, and Alzheimer's disease. This compound serves as a valuable tool for research into synaptic transmission and potential therapeutic interventions targeting nAChR-related pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Modulator |
| CAS Number | 913830-15-6 |
| Applications | α4β2 nAChR Agonist |
| Formula | C14H8N4O |
| Molecular Weight | 248.24 |
| SMILES | N#CC1=CC=CC(C2=NC(C3=CN=CC=C3)=NO2)=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.