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NSC 104999

Grb7 SH2 Domain Binder

NSC 104999 is a selective binder for the Grb7 SH2 domain, exhibiting moderate affinity with a dissociation constant (Kd) of 32.3 μM. It demonstrates significant anticancer activity, particularly against breast cancer, making it a valuable tool for research in cancer biology and therapeutic development. Researchers can utilize NSC 104999 to explore the role of Grb7 in signaling pathways and its implications in cancer progression.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	1118745-14-4
Applications	Grb7 SH2 Domain Binder
Formula	C₃₆H₄₂N₈O₄
Molecular Weight	650.77
SMILES	O=C(C1=CC=C(C(NC2=CC(C3=NCCN3)=CC(C(NCCCC)=O)=C2)=O)C=C1)NC4=CC(C5=NCCN5)=CC(C(NCCCC)=O)=C4

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.