Fig. 1 · Structure
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NSC 625987
CDK4 Inhibitor
NSC 625987 is a potent CDK4 inhibitor, exhibiting an IC50 of 0.2 μM for the CDK4:cyclin D1 complex. This compound demonstrates more than 500-fold selectivity for CDK4 compared to CDK2, making it a valuable tool for studying cell cycle regulation and cancer biology. Its specificity and efficacy make NSC 625987 suitable for research applications aimed at understanding CDK4's role in tumor proliferation and potential therapeutic strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 141992-47-4 |
| Applications | CDK4 Inhibitor |
| Formula | C15H13NO2S |
| Molecular Weight | 271.33 |
| SMILES | S=C1C2=C(C=CC=C2)NC3=C(OC)C=CC(OC)=C13 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.