Fig. 1 · Structure

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NSC 641396

RNR Inhibitor

NSC 641396 is a potent inhibitor of ribonucleotide reductase (RNR), exhibiting an IC50 value of 1.2 μM. Additionally, it serves as a selective inhibitor of protein arginine N-methyltransferase 9 (PRMT9). With demonstrated antitumor activity, NSC 641396 is valuable for research applications focusing on cancer biology and the modulation of nucleotide metabolism.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 605685-94-7
Applications RNR Inhibitor
Formula C18H13NO3
Molecular Weight 291.30
SMILES
O=C1C=CC(C2=C1C=CC3=C2N(C)C4=CC=C(OC)C=C34)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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