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NSC 645827

NQO1 Inhibitor

NSC 645827 is a selective inhibitor of NAD(P)H: quinone oxidoreductase 1 (NQO1), demonstrating an IC50 of 0.7 μM. This compound is utilized in biological research to explore the role of NQO1 in various cellular processes and its implications in cancer treatment. Its inhibitory effect on NQO1 makes it a valuable tool for studying oxidative stress responses and drug metabolism.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	128113-19-9
Applications	NQO1 Inhibitor
Formula	C₁₇H₁₇N₅O₂
Molecular Weight	323.35
SMILES	O=C1C2=CC(O)=CC=C2N3N=NC4=C3C1=C(NCCN(C)C)C=C4

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.