Fig. 1 · Structure
Documents & Downloads
NSC-77053
BoNT/E Inhibitor
NSC-77053 is a potent inhibitor of botulinum neurotoxin type E (BoNT/E), exhibiting an IC50 value of 2.4 μM and a Ki of 1.29 μM. This compound is valuable for research into neurotoxicology and the mechanisms of synaptic inhibition. It serves as a useful tool for studying neuronal pathways and developing therapeutic strategies targeting neurotoxic agents.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 77308-57-7 |
| Applications | BoNT/E Inhibitor |
| Formula | C21H14O3 |
| Molecular Weight | 314.33 |
| SMILES | O=C(C1=CC=CC=C1C(C2=CC3=C(C=C2)C(C=CC=C4)=C4C3)=O)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.