Fig. 1 · Structure
Documents & Downloads
NSC 80467
DNA Damaging Agent
NSC 80467 is a DNA damaging agent that selectively inhibits the protein survivin. This compound preferentially disrupts DNA synthesis, leading to the induction of γH2AX and pKAP1, which are established markers of DNA damage. NSC 80467 is valuable for research applications focused on cancer biology and the mechanisms of cellular response to DNA damage.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 101982-51-8 |
| Applications | DNA Damaging Agent |
| Formula | C24H22BrN3O5 |
| Molecular Weight | 512.35 |
| SMILES | O=C(C1=C2[N+](CC(C3=CC=C([N+]([O-])=O)C=C3)=O)=C(C)N1CC(C)C)C4=C(C=CC=C4)C2=O.[Br-] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.