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NSC20116

UHRF1 Inhibitor

NSC20116 is a selective inhibitor of UHRF1, targeting its Set-and-Ring (SRA) domain. This uracil derivative binds to the 5-methylcytosine recognition pocket of the UHRF1 SRA domain, exhibiting a dissociation constant (Kd) of 362 nM. NSC20116 is valuable for research into cancer mechanisms and therapeutic strategies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	644-37-1
Applications	UHRF1 Inhibitor
Formula	C₄H₄N₄O₃
Molecular Weight	156.10
SMILES	O=NNC1=CNC(NC1=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.