Fig. 1 · Structure

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NSC339614 potassium

iGluR

NSC339614 potassium acts as a selective enhancer of GluN1/GluN2C and GluN1/GluN2D NMDA receptors. This compound potentiates neuronal responses specifically through these receptor subtypes, while sparing other NMDA receptors and operating independently of L-glutamate or glycine binding. The mechanism is contingent on the unique structure of the agonist ligand binding domain, highlighting its potential as a valuable tool for investigating NMDA receptor subtype functions and developing new therapeutic strategies for neurological disorders.

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Specifications

Manufacturer Adooq Bioscience
Actions Agonist
CAS Number 1135037-53-4
Applications iGluR
Formula C10H4KN3O6S
Molecular Weight 333.32
SMILES
O=[N+](C1=CC=C2C3=NON=C3C=C(S(=O)(O[K])=O)C2=C1)[O-]

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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