Fig. 1 · Structure
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NSC622608
VISTA Ligand
NSC622608 is a ligand for the V-domain Ig suppressor of T-cell activation (VISTA), exhibiting an IC50 value of 4.8 μM. This compound plays a critical role in modulating immune responses and is utilized in research focusing on cancer immunotherapy and T-cell regulation. Its ability to influence VISTA activity makes it a valuable tool for studying immune checkpoint mechanisms and developing novel therapeutic strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2593254-90-9 |
| Applications | VISTA Ligand |
| Formula | C9H12BrN3OS2 |
| Molecular Weight | 322.25 |
| SMILES | CN(C)C1=N/C(SS1)=N/CC2=CC=CO2.Br |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.