Fig. 1 · Structure
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NSC624206
Ubiquitin E1 Inhibitor
NSC624206 is an inhibitor of ubiquitin E1 (UBA1), demonstrating an IC50 of approximately 9 μM. It specifically inhibits ubiquitin-thioester formation with an IC50 of 13 μM, while showing no significant impact on ubiquitin adenylation. This compound is valuable for research into ubiquitin-related pathways and their roles in cellular regulation and disease mechanisms.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 13116-77-3 |
| Applications | Ubiquitin E1 Inhibitor |
| Formula | C19H33Cl2NS2 |
| Molecular Weight | 410.51 |
| SMILES | CCCCCCCCCCNCCSSCC1=CC=C(Cl)C=C1.[H]Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.