Fig. 1 · Structure
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NSC668036
Dishevelled PDZ Domain Inhibitor
NSC668036 is a selective inhibitor of the Dishevelled (Dvl) PDZ domain, exhibiting a Kd of 237 μM. By disrupting the interaction between Frizzled and Dvl, NSC668036 effectively blocks Wnt signaling pathways. This compound is primarily utilized in research investigating Wnt-related processes and their implications in developmental biology and cancer.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 144678-63-7 |
| Applications | Dishevelled PDZ Domain Inhibitor |
| Formula | C21H36N2O9 |
| Molecular Weight | 460.52 |
| SMILES | C[C@@H](C(O[C@@H](C(C)C)C(N[C@@H](C)C(O[C@@H](C(C)C)C(O)=O)=O)=O)=O)NC(OC(C)(C)C)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.