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NSC682769

Ligand for Target Protein for PROTAC

NSC682769 is a ligand specifically designed for the YAP protein, serving as a critical component in the development of PROTACs (proteolysis-targeting chimeras). This compound facilitates the targeted degradation of YAP, making it a valuable tool in research focused on cellular signaling pathways and oncogenesis. NSC682769 can be utilized in the synthesis of PROTAC YAP degrader-1, enabling the exploration of targeted protein degradation strategies in cancer biology.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	205048-79-9
Applications	Ligand for Target Protein for PROTAC
Formula	C₂₇H₂₂N₂O₃
Molecular Weight	422.48
SMILES	O=C1NC2=CC=CC=C2C3=NC(C4=CC=CC=C4)=CC(C(C=C5OC)=CC=C5OC)=C3C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.