Fig. 1 · Structure
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NSD3-IN-2
NSD3 Inhibitor
NSD3-IN-2 is a selective inhibitor of NSD3, exhibiting an IC50 value of 17.97 μM. This compound demonstrates significant anti-cancer properties by inhibiting the growth and proliferation of non-small cell lung cancer cell lines, including H460, H1299, and H1650. Its role in cancer research highlights its potential as a therapeutic candidate for targeting NSD3-related pathways in oncology.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 675190-57-5 |
| Applications | NSD3 Inhibitor |
| Formula | C17H15N5OS |
| Molecular Weight | 337.40 |
| SMILES | S=C1NC2=C(N)N=CN=C2N1CCOC3=C4C=CC=CC4=CC=C3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.