Fig. 1 · Structure
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NSD3-IN-3
NSD3 Inhibitor
NSD3-IN-3 is a potent inhibitor of NSD3, demonstrating an IC50 value of 1.86 μM. This compound exhibits significant anticancer activity, effectively inhibiting the growth and proliferation of non-small cell lung cancer cell line H460. It serves as a valuable tool for studying NSD3's role in cancer biology and for developing targeted therapies against NSD3-associated malignancies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 445416-12-6 |
| Applications | NSD3 Inhibitor |
| Formula | C15H17N5O2S |
| Molecular Weight | 331.39 |
| SMILES | S=C1NC2=C(N)N=CN=C2N1CCOC3=CC=C(OCC)C=C3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.