Fig. 1 · Structure

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NT1-O12B

Brain Delivery Enhancer

NT1-O12B is a neurotransmitter-derived lipidoid that serves as a brain delivery enhancer by facilitating the transport of blood-brain barrier (BBB)-impermeable compounds. Its incorporation into lipid nanoparticles (LNPs) enables these carriers to effectively cross the BBB, allowing for enhanced delivery of therapeutic agents. NT1-O12B formulations support successful cargo delivery into neuronal cells, making it valuable for applications in functional gene silencing and gene recombination research.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 2739805-63-9
Applications Brain Delivery Enhancer
Formula C36H60N2O4S4
Molecular Weight 713.13
SMILES
CCCCCCCCSSCCOC(CCN(CCC(OCCSSCCCCCCCC)=O)CCC1=CNC2=C1C=CC=C2)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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