Fig. 1 · Structure
Documents & Downloads
NTRC 0066-0
Cat. No.
A55062
CAS
1817791-73-3
TTK Inhibitor
NTRC 0066-0 is a potent inhibitor of threonine-tyrosine kinase (TTK), exhibiting an IC50 of 0.9 nM. This selective inhibitor is valuable for cancer research, offering insights into TTK-mediated signaling pathways and their role in tumorigenesis. NTRC 0066-0 enables the exploration of TTK's contribution to cell cycle regulation and cancer cell proliferation.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1817791-73-3 |
| Applications | TTK Inhibitor |
| Formula | C33H39N7O2 |
| Molecular Weight | 565.71 |
| SMILES | O=C(C1=C2CCC3=CN=C(NC4=CC=C(N5CCN(C)CC5)C=C4OC)N=C3N2C=C1)NC6=C(CC)C=CC=C6CC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.