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NTRC-739

NTS2 Agonist

NTRC-739 is a selective nonpeptide partial agonist of the neurotensin receptor type 2 (NTS2), demonstrating an EC50 of 12 nM and a Ki of 153 nM. With a 161-fold selectivity for NTS2 over NTS1, this compound is particularly valuable for exploring mechanisms underlying chronic pain. Its targeted action on the NTS2 receptor makes it an essential tool for research in neurobiology and pain management studies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Partial Agonist
CAS Number	1612188-96-1
Applications	NTS2 Agonist
Formula	C₂₄H₂₄FN₃O₄
Molecular Weight	437.46
SMILES	O=C(C1(NC(C2=NN(C3=CC=C(F)C=C3)C(C4=CC=CC=C4OC)=C2)=O)CCCCC1)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.