Fig. 1 · Structure
Documents & Downloads
NTRC-824
NTS2 Antagonist
NTRC-824 is a selective antagonist of the neurotensin receptor type 2 (NTS2), demonstrating significant potency with an IC50 of 38 nM and a Ki of 202 nM. This compound exhibits over 150-fold selectivity for NTS2 compared to NTS1, with a Ki greater than 30 μM for NTS1. NTRC-824 is valuable for research applications aimed at exploring the physiological roles of NTS2 and investigating potential therapeutic strategies targeting neurotensin signaling pathways.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 1623002-61-8 |
| Applications | NTS2 Antagonist |
| Formula | C25H26F3N3O6S |
| Molecular Weight | 553.55 |
| SMILES | CC(C)C[C@@H](C(O)=O)NC(CN1C=C(C(C(F)(F)F)=O)C2=C1C=CC(NS(=O)(C3=CC=C(C)C=C3)=O)=C2)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.